Waters 717plus Autosampler HPLC System

The Waters 717plus Autosampler with integrated Temperature Control (Heater/Cooler) is a reliable sample introduction module for high-performance liquid chromatography (HPLC) workflows. Analytical and pharmaceutical testing laboratories rely on this unit for its durability and precision. In addition, the system automates sample aspiration and injection, which minimizes operator variability across high-throughput analytical sequences.  

Waters 717plus Autosampler Key Features

• Precision Injection System: The unit features a variable-volume syringe design. Consequently, it handles injection volumes from 0.1 µL to 2000 µL while delivering tight area reproducibility (RSD < 0.5%).  
• Active Temperature Control: An internal heater/cooler module regulates compartment temperatures from 4°C to 40°C. Therefore, it preserves unstable compounds, prevents solvent evaporation, and ensures thermal stability.  
• Sample Carousel Capacity: The carousel holds up to 96 standard 2 mL or 4 mL vials. Furthermore, operators can adapt the tray for microtiter plates and micro-vials.  
• Flexible Operating Modes: Users can operate the module directly using the front keypad and display. In addition, standard RS-232, IEEE-488 (GPIB), and contact closures support seamless integration with modern data systems.  
• Carryover Reduction: Programmable needle wash routines run between injections. As a result, this process prevents carryover and prolongs analytical column life.  

Common Applications

• Pharmaceutical QA/QC: Routine assay testing, dissolution profiling, and stability runs.  
• Bioanalytical Work: Chilled handling for temperature-sensitive proteins, peptides, and enzymes.  
• Environmental & Food Testing: Continuous screening for pesticides, additives, and target residues.

Integration and Maintenance

The Waters 717plus Autosampler features a compact footprint. Thus, it fits easily into benchtop stacks alongside HPLC isocratic or quaternary pumps, column ovens, and UV/Vis, PDA, or refractive index detectors. Moreover, the fluidics pathway handles standard reversed-phase and normal-phase solvents.

Routine maintenance remains straightforward due to direct front-panel access to the syringe, valves, and fluid lines. For laboratories upgrading older lines or seeking a dependable replacement autosampler, this instrument provides proven uptime, simple troubleshooting, and readily available replacement consumables.