Alltech 500ELSD Evaporative Light-Scattering Detector

The Alltech 500ELSD Evaporative Light-Scattering Detector serves as a reliable analytical instrument for high-performance liquid chromatography (HPLC) workflows. Unlike conventional UV/Vis detectors, which require an analyte to possess an active chromophore, an evaporative light-scattering detector operates as a universal mass detector for non-volatile and semi-volatile compounds. In addition, the Model 500 delivers stable, reproducible detection across diverse solvent gradients and operating conditions.

Alltech 500ELSD Operating Principles & Capabilities

The system processes chromatographic effluent through three distinct stages:

• Nebulization: First, the nebulizer mixes the HPLC column effluent with an inert carrier gas (typically nitrogen) to form a fine aerosol spray.
• Desolvation (Evaporation): Next, the aerosol enters a heated drift tube. Here, the mobile phase evaporates completely, leaving dry analyte particles suspended within the gas stream.
• Detection: Finally, the analyte particles flow into an optical cell illuminated by a focused light source. The particles scatter light onto a photodetector, which generates an analytical signal proportional to sample mass.

Furthermore, because the detector measures scattered light rather than optical absorption, the Alltech 500ELSD excels at analyzing challenging targets. Consequently, analysts can easily detect carbohydrates, lipids, triglycerides, polymers, surfactants, steroids, and amino acids without complex derivatization.

Core Features & Specifications

• Universal Compatibility: Offers an effective alternative or complement to refractive index (RI) and mass spectrometry detectors by measuring compounds lacking chromophores.
• Gradient Stability: Maintains a stable baseline even through complex solvent gradients that typically disrupt refractive index detection.
• Digital Controls: Features a clear front-panel digital interface that lets operators monitor and adjust drift tube temperature, gas flow, and signal output.
• System Integration: Connects smoothly with standard HPLC configurations and data acquisition setups via analog and digital ports.

Condition & Included Components

• Cosmetic Condition: The unit displays typical cosmetic wear from prior laboratory use. However, please note that the top outer cover is missing, which leaves the upper chassis exposed. Buyers may need to fabricate or source a replacement cover to comply with specific lab protocols.
• Functional State: We offer the unit as-is or pre-tested; please verify functional status and power-on test results prior to purchase.
• Accessories: The listing excludes external exhaust lines, inert gas regulators, and specialized column fittings unless pictured.

Ultimately, the Alltech 500ELSD offers a cost-effective solution for laboratories that require dependable mass-based HPLC detection where standard spectroscopic methods fall short.